More powerful CYP3A4 inhibitors including ketoconazole or itraconazole may very well be expected to have bigger outcomes than observed with saquinavir. A setting up dose of 25 mg of VIAGRA needs to be regarded as in sufferers using erythromycin or robust CYP3A4 inhibitors (including saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRA

Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) also to a lesser extent while in the urine (all over 13% on the administered oral dose). If taken having a higher-fat food, absorption is decreased; some time taken to reach the most plasma concentration will increase by around just one hour, and